Skip to content

DelayedEffect.Design

Sample Size and Power Calculations using the APPLE, SEPPLE, APPLE+ and SEPPLE+ Methods

v1.1.3 · Aug 21, 2023 · GPL-2

Description

Provides sample size and power calculations when the treatment time-lag effect is present and the lag duration is either homogeneous across the individual subject, or varies heterogeneously from individual to individual within a certain domain and following a specific pattern. The methods used are described in Xu, Z., Zhen, B., Park, Y., & Zhu, B. (2017) <doi:10.1002/sim.7157>.

Downloads

CRAN

214

Last 30 days

20790th

683

Last 90 days

2.8K

Last year

Trend: +25.2% (30d vs prior 30d)

r2u CRAN

40

Last 30 days

122

Last 90 days

426

Last year

Trend: -21.6% (30d vs prior 30d)

CRAN Check Status

2 NOTE
11 OK
Show all 13 flavors
Flavor Status
r-devel-linux-x86_64-debian-clang NOTE
r-devel-linux-x86_64-debian-gcc NOTE
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (2 non-OK)
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Bill Wheeler <wheelerb@imsweb.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Zhenzhen",
                      family = "Xu",
                      role = "aut",
                      email = "Zhenzhen.Xu@fda.hhs.gov"),
               person(given = "Boguang",
                      family = "Zhen",
                      role = "aut",
                      email = "Boguang.Zhen@fda.hhs.gov"),
               person(given = "Yongsoek",
                      family = "Park",
                      role = "aut",
                      email = "yongpark@pitt.edu"),
               person(given = "Bin",
                      family = "Zhu",
                      role = "aut",
                      email = "bin.zhu@nih.gov"),
               person(given = "Bill",
                      family = "Wheeler",
                      role = "cre",
                      email = "wheelerb@imsweb.com"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Bill Wheeler <wheelerb@imsweb.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Zhenzhen",
                      family = "Xu",
                      role = "aut",
                      email = "Zhenzhen.Xu@fda.hhs.gov"),
               person(given = "Boguang",
                      family = "Zhen",
                      role = "aut",
                      email = "Boguang.Zhen@fda.hhs.gov"),
               person(given = "Yongsoek",
                      family = "Park",
                      role = "aut",
                      email = "yongpark@pitt.edu"),
               person(given = "Bin",
                      family = "Zhu",
                      role = "aut",
                      email = "bin.zhu@nih.gov"),
               person(given = "Bill",
                      family = "Wheeler",
                      role = "cre",
                      email = "wheelerb@imsweb.com"))
as necessary.

Check History

NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Bill Wheeler <wheelerb@imsweb.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Zhenzhen",
                      family = "Xu",
                      role = "aut",
                      em
...[truncated]...
   role = "aut",
                      email = "bin.zhu@nih.gov"),
               person(given = "Bill",
                      family = "Wheeler",
                      role = "cre",
                      email = "wheelerb@imsweb.com"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Bill Wheeler <wheelerb@imsweb.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Zhenzhen",
                      family = "Xu",
                      role = "aut",
                      em
...[truncated]...
   role = "aut",
                      email = "bin.zhu@nih.gov"),
               person(given = "Bill",
                      family = "Wheeler",
                      role = "cre",
                      email = "wheelerb@imsweb.com"))
as necessary.

Version History

4 tracked
new 1.1.3 Mar 10, 2026
updated 1.1.3 ← 1.1.2 diff Aug 20, 2023
updated 1.1.2 ← 0.0.4 diff Nov 30, 2022
new 0.0.4 Aug 31, 2017