R Observatory: Metrics for DTAT version 0.3-8

Balamuta, James Joseph

doi:10.5281/zenodo.21843040

DTAT

0.3-8

Dose Titration Algorithm Tuning

0packages depend

3.4Kdownloads / year

–test coverage

13/13checks pass

Overview

About

Maintained by David C. NorrisFirst published 2019-02-189 releasesCRAN page ↗

Dose Titration Algorithm Tuning (DTAT) is a methodologic framework allowing dose individualization to be conceived as a continuous learning process that begins in early-phase clinical trials and continues throughout drug development, on into clinical practice. This package includes code that researchers may use to reproduce or extend key results of the DTAT research programme, plus tools for trialists to design and simulate a '3+3/PC' dose-finding study. Please see Norris (2017a) doi:10.12688/f1000research.10624.3 and Norris (2017c) doi:10.1101/240846.

Install

R (CRAN)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("DTAT", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-dtat

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-DTAT

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

# add the autoCRAN OBS repo (Tumbleweed) if it is missing, then install
zypper -q lr | grep -qi autoCRAN \
  || sudo zypper addrepo https://download.opensuse.org/repositories/devel:/languages:/R:/autoCRAN/openSUSE_Tumbleweed/devel:languages:R:autoCRAN.repo
sudo zypper install -y R-DTAT

RPMs auto-built from CRAN on openSUSE OBS (Tumbleweed).

Health

CRAN checks

13OK

Slowest check: 4.6 min · r-oldrel-windows-x86_64

Code health

None

Tests · ratio 0.00

not tracked

Coverage

100%

Documentation · exports

10

Dependencies · direct

Check history

OK2026-08-05
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
NOTE2026-08-01
12 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
OK2026-06-09
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-06-08
12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
OK2026-04-25
12 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Show 2 earlier snapshots

ERROR2026-03-30
13 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMENoVignettesYes · dynamicpkgdown siteNoNEWSNoCode of conductNoContributing guideNo

Examples that run: 100%
Documented parameters: 92%
Return-value docs: 70%
References docs: 33%

Downloads

3.4K

CRAN downloads in the past year

Rank #13,146 · ~9/day · ~281/mo

Releases R versions

Daily download trend is not available in this view yet.

19530 days

76690 days

3.4K1 year

Compare downloads with other packages →

Also on167 r2u17 autocran28 c2d4u

Dependencies

Declared dependencies

17 external dependencies (excludes base and recommended)

Depends (2)

R >= 3.5.0survival

Imports (9)

km.ci pomp Hmisc data.table dplyr r2d3 shiny jsonlitemethods

LinkingTo (0)

none

Suggests (10)

knitr rmarkdownlatticelatticeExtra widgetframe tidyr RColorBrewer invgamma zipfR rms

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

Datasets

People & History

People (1)

Maintainer (1)

David C. Norris

Author, Maintainer

Authors (1)

David C. Norris

Author, Maintainer

Package Timeline

9 releases. Pick two to compare their code metrics. R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
0.3-8Latest
2025-07-24 · current release · diff ↗
R
R 4.5.0 released · 2025-04-11
0.3-7
2024-05-25 · diff ↗
R
R 4.4.0 released · 2024-04-24
R
R 4.3.0 released · 2023-04-21
0.3-6
2023-03-29 · diff ↗
0.3-5
2023-03-10 · diff ↗
R
R 4.2.0 released · 2022-04-22
R
R 4.1.0 released · 2021-05-18
0.3-4
2020-06-14 · diff ↗
unarchivedReturned to CRAN
2020-06-14
R
R 4.0.0 released · 2020-04-24
archivedRemoved from CRAN
2020-04-03
check problems were not corrected in time Errors in '\donttest' parts of examples
0.3-3
2019-06-26 · diff ↗
0.3-2
2019-06-04 · diff ↗

Show 4 earlier events

R
R 3.6.0 released · 2019-04-26
0.3-1
2019-02-20 · diff ↗
0.3-0
2019-02-18
R
R 3.5.0 released · 2018-04-23

Package metadata

First published: 2019-02-18
Total releases: 9 / 7 yrs
License: MIT + file LICENSE OSI
Minimum R: ≥ 3.5.0
Bundled data: 787 KB / 2 files
Download size: 2.1 MB
Installed size: not tracked yet
With dependencies: not tracked yet

Appears in task views

Clinical Trial Design, Monitoring, Analysis and Reporting

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("DTAT")

Format

Norris, D. C. (2025). DTAT: Dose Titration Algorithm Tuning (Version 0.3-8) [Computer software]. https://doi.org/10.32614/CRAN.package.DTAT

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

Format

APA

Balamuta, J. J. (2026). R Observatory: Metrics for DTAT version 0.3-8 [Data set]. HJJB, LLC. Data release v2026-08-18. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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