DRviaSPCN
Drug Repurposing in Cancer via a Subpathway Crosstalk Network
Description
A systematic biology tool was developed to repurpose drugs via a subpathway crosstalk network. The operation modes include 1) calculating centrality scores of SPs in the context of gene expression data to reflect the influence of SP crosstalk, 2) evaluating drug-disease reverse association based on disease- and drug-induced SPs weighted by the SP crosstalk, 3) identifying cancer candidate drugs through perturbation analysis. There are also several functions used to visualize the results.
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CRAN Check Status
Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | OK |
| r-devel-linux-x86_64-debian-gcc | OK |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | NOTE |
| r-oldrel-macos-x86_64 | NOTE |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | ERROR |
Check details (3 non-OK)
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb
whether package can be installed
Installation failed. See 'd:/Rcompile/CRANpkg/local/4.5/DRviaSPCN.Rcheck/00install.out' for details.
Check History
ERROR 11 OK · 2 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Mar 30, 2026
whether package can be installed
Installation failed. See 'd:/Rcompile/CRANpkg/local/4.5/DRviaSPCN.Rcheck/00install.out' for details.
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb
NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 16, 2026
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb
ERROR 11 OK · 2 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Mar 10, 2026
package dependencies
Package required but not available: ‘clusterProfiler’ See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’ manual.
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 5.4Mb