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DANDELION

0.1.0Package record

Discovery of Candidate Disease Genes Using Trans-Regulatory Effects

0packages depend
1.2Kdownloads / year
–test coverage
13/13flavors OK

Overview

About

Implements the DANDELION method for prioritizing candidate disease-related proximal genes by integrating trans-regulatory association p-values and gene-level trait association p-values. The statistical testing framework builds on the divide-aggregate composite-null test described by Liu et al. (2022) doi:10.1080/01621459.2021.1914634. The biological application and SNP/gene-based prioritization workflow are motivated by Salamone et al. (under review), "Leveraging trans-gene regulation prioritizes central genes and pathways in asthma". The package provides functions for identifying distal-proximal gene pairs, organizing significant pairs into genomic loci, and visualizing resulting gene networks.

Install

Health

CRAN checks
13OK
Slowest check: 53 s · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK13 OK2026-07-28
  • NOTE12 OK, 1 NOTE2026-07-27
  • OK6 OK2026-05-05
Advisories

none known

Documentation

In release 0.1.0
READMENoVignettesNoNEWSNoCitation fileNoWebsitenot declared in DESCRIPTION
Help pages
7 (1 internal)
Examples that run
100%1 run in a plain check
Exported functions with examples
25%
Documented parameters
100%
Return-value docs
100%
Help pages citing references
0%

Downloads

1.2K
CRAN downloads in the past year
Rank #21,380 · ~3/day · ~96/mo
Daily download trend is not available in this view yet.
23330 days
61490 days
1.2K1 year
Compare downloads with other packages →
Also on31 r2u8 autocran

Dependencies

Declared dependencies
2 external dependencies (excludes base and recommended)

Installing DANDELION adds 9 packages (6 with compiled code, 8.0 MB of source tarballs). Heaviest: igraph 4.8 MB, vctrs 1.0 MB, rlang 766 KB.

Depends (0)
none
Imports (1)
LinkingTo (0)
none
Suggests (1)
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

People & History

People (1)
Author, Maintainer since 0.1.0 (2026)
Releases (1)
  • 0.1.0Latest
    2026-05-04 · current release
  • R
    R 4.6.0 released · 2026-04-24

Package metadata

First published
2026-05-04
Total releases
1 / 1 yrs
License
GPL-3 OSI
Additional repositories
bioconductor.org
Download size
11 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("DANDELION")
Tian, P. (2026). DANDELION: Discovery of Candidate Disease Genes Using Trans-Regulatory Effects (Version 0.1.0) [Computer software]. https://doi.org/10.32614/CRAN.package.DANDELION

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for DANDELION version 0.1.0 [Data set]. HJJB, LLC. Data release v2026-10-19. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-19, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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