Clonality Estimates in Tumor
Overview
Analyze data from next-generation sequencing experiments on genomic samples. 'CLONETv2' offers a set of functions to compute allele specific copy number and clonality from segmented data and SNPs position pileup. The package has also calculated the clonality of single nucleotide variants given read counts at mutated positions. The package has been developed at the laboratory of Computational and Functional Oncology, Department of CIBIO, University of Trento (Italy), under the supervision of prof Francesca Demichelis. References: Prandi et al. (2014) doi:10.1186/s13059-014-0439-6; Carreira et al. (2014) doi:10.1126/scitranslmed.3009448; Romanel et al. (2015) doi:10.1126/scitranslmed.aac9511.
- Set lower bound for corrected CN ratio (this solves issues for homozygous calls in noisy samples).
From NEWS.md in the release
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK14 OK2026-03-10
Documentation
- Help pages
- 19includes a package overview page
- Examples that run
- 63%5 run in a plain check · 3 only when donttest examples are enabled (R CMD check --as-cran)
- Exported functions with examples
- 39%
- Documented parameters
- 97%
- Return-value docs
- 39%
- Help pages citing references
- 5%
Downloads
Dependencies
Code & Tests
People & History
Previously maintained by Davide Prandi (2.0 to 2.1.0).
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- 2.2.1Latest
- RR 4.1.0 released · 2021-05-18
- RR 4.0.0 released · 2020-04-24
- 2.1.02019-05-20 · diff ↗
- RR 3.6.0 released · 2019-04-26
- 2.02019-04-05
- RR 3.5.0 released · 2018-04-23
Package metadata
- First published
- 2019-04-05
- Total releases
- 3 / 7 yrs
- License
- MIT + file LICENSE OSI
- Minimum R
- ≥ 3.1
- Download size
- 2.6 MB
Cite
Cite this package
Run in R for the authors' preferred citation:
citation("CLONETv2")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
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