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BioM2

Biologically Explainable Machine Learning Framework

v1.1.3 · Jul 17, 2025 · MIT + file LICENSE

Description

Biologically Explainable Machine Learning Framework for Phenotype Prediction using omics data described in Chen and Schwarz (2017) <doi:10.48550/arXiv.1712.00336>.Identifying reproducible and interpretable biological patterns from high-dimensional omics data is a critical factor in understanding the risk mechanism of complex disease. As such, explainable machine learning can offer biological insight in addition to personalized risk scoring.In this process, a feature space of biological pathways will be generated, and the feature space can also be subsequently analyzed using WGCNA (Described in Horvath and Zhang (2005) <doi:10.2202/1544-6115.1128> and Langfelder and Horvath (2008) <doi:10.1186/1471-2105-9-559> ) methods.

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CRAN Check Status

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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
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r-release-macos-arm64 OK
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r-release-windows-x86_64 OK

Check History

OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 9, 2026
ERROR 12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Jun 8, 2026
ERROR r-devel-linux-x86_64-debian-gcc

package dependencies

Packages required but not available:
  'WGCNA', 'caret', 'ggpubr', 'ggstatsplot', 'ggnetwork'

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE May 2, 2026
ERROR 11 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Apr 25, 2026
ERROR r-release-macos-x86_64

package dependencies

Package required but not available: ‘caret’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Apr 10, 2026
ERROR 13 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Apr 9, 2026
ERROR r-devel-linux-x86_64-debian-gcc

package dependencies

Package required but not available: ‘uwot’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Code

Structure

Lines of code

3,416

Files

36

Compiled share

0%

Has compiled src

No

Language breakdown

R 2,457 (71.9%)Docs 959 (28.1%)

API

Exported functions

14

Internal functions

0

Testing & CI

Has tests

No

Test-to-code ratio

0.00

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Return-value doc rate

100%

\dontrun example ratio

0%

Roxygen coverage

100%

Has pkgdown

No

NEWS present

Yes

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

6

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.1.0

System requirements

C++ standard

License

MIT + file LICENSE

License flags

SPDX valid, OSI approved

History

Versions

15

First release

2023-09-21

Latest release

2025-07-17

Avg cadence

35 days

Cold removal rate

100%

Dep drift

14

LOC over versions

v1.0: 2,040 LOCv1.0.1: 2,148 LOCv1.0.2: 2,781 LOCv1.0.3: 2,843 LOCv1.0.4: 2,851 LOCv1.0.5: 2,851 LOCv1.0.6: 2,851 LOCv1.0.7: 3,186 LOCv1.0.8: 3,561 LOCv1.0.9: 3,561 LOCv1.0.10: 3,288 LOCv1.1.0: 3,377 LOCv1.1.1: 3,404 LOCv1.1.2: 3,403 LOCv1.1.3: 3,416 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/cran-code-metrics.

Dependency Network

Dependencies Reverse dependencies WGCNA mlr3 CMplot ggsci ROCR caret ggplot2 ggpubr viridis ggthemes ggstatsplot htmlwidgets mlr3verse uwot webshot +4 more dependencies BioM2

Version History

16 tracked
new 1.1.3 Mar 10, 2026
updated 1.1.3 ← 1.1.2 diff Jul 16, 2025
updated 1.1.2 ← 1.1.1 diff May 13, 2025
updated 1.1.1 ← 1.1.0 diff Feb 18, 2025
updated 1.1.0 ← 1.0.10 diff Sep 19, 2024
updated 1.0.10 ← 1.0.9 diff Aug 19, 2024
updated 1.0.9 ← 1.0.8 diff Jul 31, 2024
updated 1.0.8 ← 1.0.7 diff Jul 17, 2024
updated 1.0.7 ← 1.0.6 diff Jun 8, 2024
updated 1.0.6 ← 1.0.5 diff May 15, 2024
updated 1.0.5 ← 1.0.4 diff Mar 9, 2024
updated 1.0.4 ← 1.0.3 diff Feb 28, 2024
updated 1.0.3 ← 1.0.2 diff Jan 10, 2024
updated 1.0.2 ← 1.0.1 diff Oct 24, 2023
updated 1.0.1 ← 1.0 diff Sep 26, 2023