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BBMBC

0.1.0Package record

Beta-Binomial Models for Vaccine-Specific Memory B Cell Frequency and Power Calculations

0packages depend
150downloads / year
95.8%test coverage
13/13flavors OK

Overview

About

Provides tools to model overdispersed vaccine-specific memory B cell frequencies using Beta-Binomial generalized linear models, specifically designed for analyzing vaccine-induced cellular immune responses. Includes method-of-moments dispersion estimation, likelihood ratio testing across experimental arms, and Monte Carlo simulation frameworks to calculate statistical power and Type I error rates. The methodologies are directly motivated by the analysis of immunology data in 'Vaccination with mRNA-encoded membrane-anchored HIV envelope trimers elicited tier 2 neutralizing antibodies in a phase 1 clinical trial' (Parks et al. 2025) doi:10.1126/scitranslmed.ady6831.

Install

Health

CRAN checks
13OK
Slowest check: 2.9 min · r-release-macos-x86_64
Status changes
  • OK13 OKNow
  • OK3 OK2026-10-07
Advisories

none known

Documentation

In release 0.1.0
READMENoVignettesNoNEWSNoCitation fileNoWebsitenot declared in DESCRIPTION
Help pages
5 (1 internal)includes a package overview page
Examples that run
50%2 run in a plain check · 2 only when donttest examples are enabled (R CMD check --as-cran)
Exported functions with examples
100%
Documented parameters
93%
Return-value docs
100%
Help pages citing references
0%

Downloads

150
CRAN downloads in the past year
Rank #25,455 · ~0/day · ~13/mo
Daily download trend is not available in this view yet.
15030 days
15090 days
1501 year
Compare downloads with other packages →
Also on5 autocran

Dependencies

Declared dependencies
4 external dependencies (excludes base and recommended)

Installing BBMBC adds 60 packages (33 with compiled code, 60 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, glmmTMB 5.2 MB.

Depends (1)
R >= 4.1.0
Imports (6)
doParallelforeachglmmTMBparallelstatsutils
LinkingTo (0)
none
Suggests (1)
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

People & History

People (1)
Author, Maintainer since 0.1.0 (2026)
Releases (1)
  • 0.1.0Latest
    2026-10-07 · current release ·
    3 days in CRAN's queue
    Listed in CRAN's incoming queue from 2026-10-03 21:57 to 2026-10-07 06:45 UTC, in 16 readings.
  • R
    R 4.6.0 released · 2026-04-24
Across CRAN, the median accepted release of the past year spent 19 hours in the queue, 90% under 11 days.How queue time is measured

Package metadata

First published
2026-10-07
Total releases
1 / 1 yrs
License
MIT + file LICENSE OSI
Minimum R
≥ 4.1.0
Download size
8.9 KB

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("BBMBC")
Shin, A. (2026). BBMBC: Beta-Binomial Models for Vaccine-Specific Memory B Cell Frequency and Power Calculations (Version 0.1.0) [Computer software]. https://doi.org/10.32614/CRAN.package.BBMBC

This package has no citation file, so citation() returns this entry built from DESCRIPTION.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for BBMBC version 0.1.0 [Data set]. HJJB, LLC. Data release v2026-10-17. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-17, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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