AdaptiveTrialsR

0.1.2

Bayesian and Adaptive Clinical Trial Simulation and Monitoring

0packages depend

18downloads / year

–test coverage

10/11checks pass

Overview

About

Maintained by Muhammad Zahir KhanFirst published 2026-07-301 releasesCRAN page ↗GitHub ↗

Provides tools for simulating, monitoring, and evaluating Bayesian and adaptive clinical trial designs with binary outcomes. The package includes methods for trial simulation, posterior and predictive probability monitoring, adaptive randomization, Bayesian treatment-effect estimation, dose-finding designs, two-stage phase II trial designs, group sequential monitoring, operating-characteristic evaluation, interim analyses, and decision-support procedures. The methodological foundation includes the two-stage phase II design described by Simon (1989) doi:10.1016/0197-2456(89)90015-9.

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)

install.packages("AdaptiveTrialsR", repos = "https://cloud.r-project.org/")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

if (!requireNamespace("pak", quietly = TRUE))
  install.packages("pak", repos = "https://cloud.r-project.org/")
pak::pak("zerish12/AdaptiveTrialsR")

Development version from zerish12/AdaptiveTrialsR. Installs pak first if it is not already available.

Release

# enable cranapt (r2u) if it is not already set up, then install
grep -rqs r2u.stat.illinois.edu /etc/apt/sources.list /etc/apt/sources.list.d/ \
  || curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash
sudo apt install -y r-cran-adaptivetrialsr

Fast Ubuntu binaries via r2u (no compilation). The cranapt setup runs once and is skipped when it is already enabled.

bspm (used by r2u) also needs make: sudo apt install make

# enable the iucar/cran COPR if it is not already present, then install
ls /etc/yum.repos.d/*iucar*cran*.repo >/dev/null 2>&1 \
  || sudo dnf copr enable -y iucar/cran
sudo dnf install -y R-CRAN-AdaptiveTrialsR

RPMs from the iucar/cran COPR, rebuilt from CRAN.

For install.packages() integration in R, also: sudo dnf install R-CoprManager

Health

CRAN checks

1NOTE10OK

Failing flavors

NOTE r-devel-linux-x86_64-debian-gcc

Slowest check: 1.5 min · r-release-windows-x86_64

Code health

None

Tests · ratio 0.00

not tracked

Coverage

100%

Documentation · exports

Dependencies · direct

Check history

NOTE2026-08-01
9 OK · 1 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
OK2026-07-31
7 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Documentation

READMEYes · 42 wordsVignettesNopkgdown siteNoNEWSNoCode of conductNoContributing guideNo

Examples that run: 100%
Documented parameters: 99%
Return-value docs: 100%
References docs: 3%

Downloads

CRAN downloads in the past year

Rank #24,667 · ~0/day · ~2/mo

Releases R versions

Daily download trend is not available in this view yet.

1830 days

1890 days

181 year

Compare downloads with other packages →

Also on3 r2u

Repository

GitHub ↗ zerish12/adaptivetrialsr

0Stars

0Forks

0Open issues

0Open PRs

0Releases

Last activity 2026-06-10

Repository practices

Upstream repositoryBeta

1 development-tooling and community-health practice detected across 1 family in the upstream repository

Checks run against github.com/zerish12/adaptivetrialsr on 2026-08-02.

Lint, format, editor (1)

RStudio project

How this is detected·Detection ruleset v1 (2026-07-18)

Dependencies

Declared dependencies

4 external dependencies (excludes base and recommended)

Depends (0)

none

Imports (5)

statsutilsdplyr ggplot2 rlang

LinkingTo (0)

none

Suggests (1)

testthat

Enhances (0)

none

Dependency license breakdown →

Reverse dependencies

0direct

0indirect

Nothing depends on this yet.

Code & Tests

People & History

People (1)

Maintainer (1)

Muhammad Zahir Khan

Author, Maintainer

Authors (1)

Muhammad Zahir Khan

Author, Maintainer

Package Timeline

1 release. R releases are shown for context.

0.1.2Latest
2026-07-30 · current release
R
R 4.6.0 released · 2026-04-24

Package metadata

First published: 2026-07-30
Total releases: 1 / 1 yrs
License: MIT + file LICENSE OSI
Download size: not tracked yet
Installed size: not tracked yet
With dependencies: not tracked yet

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