chipseqDB
Bioc currentA Bioconductor Workflow to Detect Differential Binding in ChIP-seq Data
Release Lineage
Entered 3.2 · Oct 14, 2015
Current · Requires R 4.6
Description
Describes a computational workflow for performing a DB analysis with sliding windows. The aim is to facilitate the practical implementation of window-based DB analyses by providing detailed code and expected output. The workflow described here applies to any ChIP-seq experiment with multiple experimental conditions and multiple biological samples in one or more of the conditions. It detects and summarizes DB regions between conditions in a de novo manner, i.e., without making any prior assumptions about the location or width of bound regions. Detected regions are then annotated according to their proximity to genes.
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People
- Aaron Lun author maintainer
- Gordon Smyth author