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MSstatsResponse

Bioc current

Statistical Methods for Chemoproteomics Dose-Response Analysis

v1.2.0 · software · Artistic-2.0

Release Lineage

Entered 3.22 · Oct 30, 2025

Current · Requires R 4.6

1.0 In 2 of 49 releases 3.23

Description

Tools for detecting drug-protein interactions and estimating IC50 values from chemoproteomics data. Implements semi-parametric isotonic regression, bootstrapping, and curve fitting to evaluate compound effects on protein abundance.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

27 11 exported

Complexity

8 avg / 36 max

Call network

27 nodes / 28 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

6,500

Files

52

Compiled share

0%

Has compiled src

No

Language breakdown

R 3,093 (47.6%)Tests 1,603 (24.7%)Docs 1,398 (21.5%)Vignettes 406 (6.2%)

API

Exported functions

11

Internal functions

16

Recent export changes

v3.23+4 calculatePeptideWeights, calculateTurnoverRatios, plot_tpr_power_curve +1 more
v3.22+7 MSstatsPrepareDoseResponseFit, convertGroupToNumericDose, doseResponseFit +4 more

Testing & CI

Has tests

Yes

Test-to-code ratio

0.52

testthat edition

CI present

Yes

CI type

["github-actions"]

PR gated

Yes

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

0%

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

4.5.0

System requirements

C++ standard

License

Artistic-2.0

License flags

SPDX valid, OSI approved

History

Versions

2

First release

2025-10-29

Latest release

2026-04-28

Avg cadence

181 days

Cold removal rate

Dep drift

4

LOC over versions

v3.22: 4,598 LOCv3.23: 6,500 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 118 wordsVignettesYes · dynamicpkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
69%
Documented parameters
95%
Return-value docs
100%
References docs
0%

Topics

Depended on by (1)

Bioconductor (1)

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("MSstatsResponse")
Szvetecz, S., Kohler, D., Vitek, O., & Wu, T. (2026). MSstatsResponse: Statistical Methods for Chemoproteomics Dose-Response Analysis (Version 1.2.0) [Computer software]. https://bioconductor.org/packages/MSstatsResponse

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for MSstatsResponse version 1.2.0 [Data set]. HJJB, LLC. Data release v2026-08-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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