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BUSseq

Bioc current

Batch Effect Correction with Unknow Subtypes for scRNA-seq data

v1.18.0 · software · Artistic-2.0

Release Lineage

Entered 3.14 · Oct 27, 2021

Current · Requires R 4.6

1.0 In 10 of 49 releases 3.23

Description

BUSseq R package fits an interpretable Bayesian hierarchical model---the Batch Effects Correction with Unknown Subtypes for scRNA seq Data (BUSseq)---to correct batch effects in the presence of unknown cell types. BUSseq is able to simultaneously correct batch effects, clusters cell types, and takes care of the count data nature, the overdispersion, the dropout events, and the cell-specific sequencing depth of scRNA-seq data. After correcting the batch effects with BUSseq, the corrected value can be used for downstream analysis as if all cells were sequenced in a single batch. BUSseq can integrate read count matrices obtained from different scRNA-seq platforms and allow cell types to be measured in some but not all of the batches as long as the experimental design fulfills the conditions listed in our manuscript.

Test coverage

Line coverage

Expression

Tests / Examples

Functions

88 15 exported

Complexity

4.5 avg / 15 max

Call network

88 nodes / 55 edges

Test coverage is not measured for Bioconductor packages; nodes fall back to a neutral fill.

Loading call graph…

Lowest coverage

Per-function coverage is not measured for this package yet.

Code

Structure

Lines of code

6,795

Files

34

Compiled share

64.3%

Has compiled src

Yes

Language breakdown

R 599 (8.8%)C/C++/src 4,368 (64.3%)Tests 70 (1%)Docs 1,117 (16.4%)Vignettes 641 (9.4%)

API

Exported functions

15

Internal functions

0

Testing & CI

Has tests

Yes

Test-to-code ratio

0.12

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Roxygen coverage

100%

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

3.6

System requirements

C++ standard

C++11

License

Artistic-2.0

License flags

SPDX valid, OSI approved

History

Versions

10

First release

2021-10-26

Latest release

2026-04-28

Avg cadence

182 days

Cold removal rate

Dep drift

0

LOC over versions

v3.14: 6,795 LOCv3.15: 6,795 LOCv3.16: 6,795 LOCv3.17: 6,795 LOCv3.18: 6,795 LOCv3.19: 6,795 LOCv3.20: 6,795 LOCv3.21: 6,795 LOCv3.22: 6,795 LOCv3.23: 6,795 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/bioc-code-metrics.

Documentation

Documentation
READMEYes · 667 wordsVignettesYes · dynamicpkgdown siteNoNEWSNoCode of conductNoContributing guideNo
Examples that run
82%
Documented parameters
99%
Return-value docs
100%
References docs
100%

Topics

People

Cite

Cite this package

Run in R for the authors' preferred citation:

citation("BUSseq")
Song, F., Chan, G. M., & Wei, Y. (2026). BUSseq: Batch Effect Correction with Unknow Subtypes for scRNA-seq data (Version 1.18.0) [Computer software]. https://bioconductor.org/packages/BUSseq

This is what citation() produces when a package has no citation file of its own. If it prints something else, use that.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for BUSseq version 1.18.0 [Data set]. HJJB, LLC. Data release v2026-08-24. https://doi.org/10.5281/zenodo.21843040

From data release v2026-08-24, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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