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wTO

Computing Weighted Topological Overlaps (wTO) & Consensus wTO Network

v2.1 · Jul 4, 2024 · GPL-2

Description

Computes the Weighted Topological Overlap with positive and negative signs (wTO) networks given a data frame containing the mRNA count/ expression/ abundance per sample, and a vector containing the interested nodes of interaction (a subset of the elements of the full data frame). It also computes the cut-off threshold or p-value based on the individuals bootstrap or the values reshuffle per individual. It also allows the construction of a consensus network, based on multiple wTO networks. The package includes a visualization tool for the networks. More about the methodology can be found at <doi:10.1186/s12859-018-2351-7>.

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CRAN incoming feasibility

Maintainer: ‘Deisy Morselli Gysi <deisy.ccnr@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = c("Deisy", "Morselli"),
                      family = "Gysi",
                      role = c("aut", "cre"),
                      email = "deisy.ccnr@gmail.com"),
               person(given = "Andre",
                      family = "Voigt",
                      role = "aut"),
               person(given = c("Tiago", "Miranda"),
                      family = "Fragoso",
                      role = "aut"),
               person(given = "Eivind",
                      family = "Almaas",
                      role = "aut"),
               person(given = "Katja",
                      family = "Nowick.",
                      role = "aut"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Deisy Morselli Gysi <deisy.ccnr@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = c("Deisy", "Morselli"),
                      family = "Gysi",
                      role = c("aut", "cre"),
                      email = "deisy.ccnr@gmail.com"),
               person(given = "Andre",
                      family = "Voigt",
                      role = "aut"),
               person(given = c("Tiago", "Miranda"),
                      family = "Fragoso",
                      role = "aut"),
               person(given = "Eivind",
                      family = "Almaas",
                      role = "aut"),
               person(given = "Katja",
                      family = "Nowick.",
                      role = "aut"))
as necessary.

Check History

NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Deisy Morselli Gysi <deisy.ccnr@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = c("Deisy", "Morselli"),
                      family = "Gysi",
                      role = c("aut", 
...[truncated]...

               person(given = "Eivind",
                      family = "Almaas",
                      role = "aut"),
               person(given = "Katja",
                      family = "Nowick.",
                      role = "aut"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Deisy Morselli Gysi <deisy.ccnr@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = c("Deisy", "Morselli"),
                      family = "Gysi",
                      role = c("aut", 
...[truncated]...

               person(given = "Eivind",
                      family = "Almaas",
                      role = "aut"),
               person(given = "Katja",
                      family = "Nowick.",
                      role = "aut"))
as necessary.

Reverse Dependencies (2)

imports

suggests

Dependency Network

Dependencies Reverse dependencies data.table igraph magrittr plyr som visNetwork reshape2 Rfast HiClimR NetSci CoDiNA wTO

Version History

new 2.1 Mar 10, 2026
updated 2.1 ← 2.0.2 diff Jul 4, 2024
updated 2.0.2 ← 2.0.1 diff Mar 21, 2023
updated 2.0.1 ← 2.0 diff May 23, 2022
updated 2.0 ← 1.6.3 diff May 10, 2022
updated 1.6.3 ← 1.6.2 diff Nov 16, 2018
updated 1.6.2 ← 1.6.1 diff Oct 13, 2018
updated 1.6.1 ← 1.6 diff Jun 27, 2018
updated 1.6 ← 1.5 diff May 29, 2018
updated 1.5 ← 1.4.2 diff Mar 1, 2018
updated 1.4.2 ← 1.4.1 diff Jan 31, 2018
updated 1.4.1 ← 1.4.0 diff Nov 21, 2017
updated 1.4.0 ← 1.3.0 diff Nov 11, 2017
updated 1.3.0 ← 1.2.2 diff Oct 3, 2017
updated 1.2.2 ← 1.2.0 diff Jul 15, 2017
updated 1.2.0 ← 1.1.0 diff Jun 7, 2017
new 1.1.0 May 28, 2017