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Optimal Sample Size and Progression Criteria for Three-Outcome Trials

v1.0.3 · Nov 7, 2025 · MIT + file LICENSE

Description

Find the optimal decision rules (AKA progression criteria) and sample size for clinical trials with three (stop/pause/go) outcomes. Both binary and continuous endpoints can be accommodated, as can cases where an adjustment is planned following a pause outcome. For more details see Wilson et al. (2024) <doi:10.1186/s12874-024-02351-x>.

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r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Version History

new 1.0.3 Mar 10, 2026