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tcplfit2

A Concentration-Response Modeling Utility

v0.1.9 · Jul 23, 2025 · MIT + file LICENSE
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Description

The tcplfit2 R package performs basic concentration-response curve fitting. The original tcplFit() function in the tcpl R package performed basic concentration-response curvefitting to 3 models. With tcplfit2, the core tcpl concentration-response functionality has been expanded to process diverse high-throughput screen (HTS) data generated at the US Environmental Protection Agency, including targeted ToxCast, high-throughput transcriptomics (HTTr) and high-throughput phenotypic profiling (HTPP). tcplfit2 can be used independently to support analysis for diverse chemical screening efforts.

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CRAN Check Status

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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Reverse Dependencies (1)

imports

tcpl

Dependency Network

Dependencies Reverse dependencies numDeriv RColorBrewer stringr reshape2 ggplot2 tcpl tcplfit2

Version History

new 0.1.9 Mar 10, 2026
updated 0.1.9 ← 0.1.8 diff Jul 22, 2025
updated 0.1.8 ← 0.1.7 diff Apr 16, 2025
updated 0.1.7 ← 0.1.6 diff Sep 23, 2024
updated 0.1.6 ← 0.1.5 diff Oct 9, 2023
updated 0.1.5 ← 0.1.3 diff Apr 5, 2023
updated 0.1.3 ← 0.1.2 diff Oct 12, 2021
updated 0.1.2 ← 0.1.1 diff Sep 30, 2021
new 0.1.1 Jul 13, 2021