simaerep

1.0.0

Detect Clinical Trial Sites Over- or Under-Reporting Clinical Events

0packages depend

3.1Kdownloads / year

–test coverage

13/13checks pass

Overview

About

Maintained by Bjoern KoneswarakanthaFirst published 2023-02-256 releasesCRAN page ↗GitHub ↗

Monitoring reporting rates of subject-level clinical events (e.g. adverse events, protocol deviations) reported by clinical trial sites is an important aspect of risk-based quality monitoring strategy. Sites that are under-reporting or over-reporting events can be detected using bootstrap simulations during which patients are redistributed between sites. Site-specific distributions of event reporting rates are generated that are used to assign probabilities to the observed reporting rates. (Koneswarakantha 2024 <doi:10.1007/s43441-024-00631-8>).

Install

R (CRAN)pak (dev)Ubuntu (r2u)Fedora (COPR)openSUSE (OBS)

install.packages("simaerep")

Installs the current CRAN release. Prebuilt binaries on Windows and macOS.

pak::pak("openpharma/simaerep")

Development version from openpharma/simaerep. Requires the pak package.

Release

# one-time r2u setup for Ubuntu (noble)

curl -fsSL https://raw.githubusercontent.com/eddelbuettel/r2u/master/inst/scripts/add_cranapt_noble.sh | sudo bash

# then install

sudo apt install r-cran-simaerep

Fast Ubuntu binaries via r2u (no compilation). Run the setup once per machine.

bspm (used by r2u) also needs make: sudo apt install make

sudo dnf copr enable iucar/cran

sudo dnf install R-CRAN-simaerep

RPMs from the iucar/cran COPR, rebuilt from CRAN.

sudo zypper install R-simaerep

RPMs auto-built from CRAN on openSUSE OBS.

Health

CRAN checks

13OK

Code health

Yes

Tests · ratio 0.93

not tracked

Coverage

95%

Documentation · exports

None

Vignettes

Yes

README

Dependencies · direct

Check history

OK2026-06-09
13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
ERROR2026-06-08
12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
OK2026-03-10
14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE

Downloads

3.1K

CRAN downloads in the past year

Rank #14,266 · ~8/day · ~255/mo

33830 days

76790 days

3.1K1 year

Also on112 r2u14 autocran

Source & community

GitHub ↗

Repository stars, issues, and contributor activity are not tracked yet.

Dependencies

Declared dependencies

26 external dependencies (excludes base and recommended)

Depends (2)

R >= 4.0ggplot2

Imports (15)

dplyr tidyr magrittr purrr rlang stringr forcats cowplot RColorBrewer furrr progressr knitr tibble dbplyr glue

LinkingTo (0)

none

Suggests (10)

testthat devtools pkgdown spelling haven vdiffr lintr DBI duckdb ggExtra

Enhances (0)

none

Reverse dependencies

0direct

–indirect (not tracked)

Nothing depends on this yet.

Code

8,474Lines of code

22Exported functions

Code & tests

Open call graph →

Code intelligence has not been computed for this package yet.

People & History

People (2)

Maintainer (1)

Bjoern Koneswarakantha iD

Author, Maintainer, Copyright holder

F. Hoffmann-La Roche Ltd

Release timeline

6 releases. Pick two to compare their code metrics; R releases are shown for context.

R
R 4.6.0 released · 2026-04-24
1.0.0Latest
2025-10-28 · current release
R
R 4.5.0 released · 2025-04-11
0.7.0
2025-04-09 · diff ↗
0.6.0
2024-09-30 · diff ↗
R
R 4.4.0 released · 2024-04-24
0.5.0
2024-04-03 · diff ↗
R
R 4.3.0 released · 2023-04-21
0.4.3
2023-03-03 · diff ↗
0.4.2
2023-02-25

Package metadata

First published: 2023-02-25
Total releases: 6 / 3 yrs
License: MIT + file LICENSE OSI
Download size: not tracked yet
Installed size: not tracked yet
With dependencies: not tracked yet