simFastBOIN
Fast Bayesian Optimal Interval Design for Phase I Dose-Finding Trials
Description
Conducting Bayesian Optimal Interval (BOIN) design for phase I dose-finding trials. 'simFastBOIN' provides functions for pre-computing decision tables, conducting trial simulations, and evaluating operating characteristics. The package uses vectorized operations and the Iso::pava() function for isotonic regression to achieve efficient performance while maintaining full compatibility with BOIN methodology. Version 1.3.2 adds p_saf and p_tox parameters for customizable safety and toxicity thresholds. Version 1.3.1 fixes Date field. Version 1.2.1 adds comprehensive 'roxygen2' documentation and enhanced print formatting with flexible table output options. Version 1.2.0 integrated C-based PAVA for isotonic regression. Version 1.1.0 introduced conservative MTD selection (boundMTD) and flexible early stopping rules (n_earlystop_rule). Methods are described in Liu and Yuan (2015) <doi:10.1111/rssc.12089>.
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CRAN Check Status
Show all 13 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | OK |
| r-devel-linux-x86_64-debian-gcc | OK |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check History
OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 8, 2026
WARNING 12 OK · 0 NOTE · 1 WARNING · 0 ERROR · 0 FAILURE Jun 7, 2026
top-level files
Conversion of ‘README.md’ failed: pandoc: /tmp/Rtmp1KP89q/pandocfe5c7143350eb.html: withFile: resource exhausted (No space left on device) HasCallStack backtrace: collectBacktraces, called at libraries/ghc-internal/src/GHC/Internal/Exception.hs:169 ...[truncated]... owIO, called at libraries/ghc-internal/src/GHC/Internal/IO/Exception.hs:315:19 in ghc-internal:GHC.Internal.IO.Exception ioException, called at libraries/ghc-internal/src/GHC/Internal/IO/Exception.hs:319:20 in ghc-internal:GHC.Internal.IO.Exception
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
Dependency Network
Version History
1 trackedR Observatory began tracking this package on Mar 10, 2026; it first appeared on CRAN Dec 17, 2025. Releases before tracking aren’t shown.