Description
Contains utilities for the analysis of Michaelian kinetic data. Beside the classical linearization methods (Lineweaver-Burk, Eadie-Hofstee, Hanes-Woolf and Eisenthal-Cornish-Bowden), features include the ability to carry out weighted regression analysis that, in most cases, substantially improves the estimation of kinetic parameters (Aledo (2021) <doi:10.1002/bmb.21522>). To avoid data transformation and the potential biases introduced by them, the package also offers functions to directly fitting data to the Michaelis-Menten equation, either using ([S], v) or (time, [S]) data. Utilities to simulate substrate progress-curves (making use of the Lambert W function) are also provided. The package is accompanied of vignettes that aim to orientate the user in the choice of the most suitable method to estimate the kinetic parameter of an Michaelian enzyme.
Downloads
280
Last 30 days
14945th
805
Last 90 days
3.1K
Last year
Trend: -4.4% (30d vs prior 30d)
CRAN Check Status
Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | NOTE |
| r-devel-linux-x86_64-debian-gcc | NOTE |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check details (2 non-OK)
CRAN incoming feasibility
Maintainer: ‘Juan Carlos Aledo <caledo@uma.es>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = c("Juan", "Carlos"),
family = "Aledo",
role = c("aut", "cre"),
email = "caledo@uma.es")
as necessary.
CRAN incoming feasibility
Maintainer: ‘Juan Carlos Aledo <caledo@uma.es>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = c("Juan", "Carlos"),
family = "Aledo",
role = c("aut", "cre"),
email = "caledo@uma.es")
as necessary.
Check History
NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
CRAN incoming feasibility
Maintainer: ‘Juan Carlos Aledo <caledo@uma.es>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = c("Juan", "Carlos"),
family = "Aledo",
role = c("aut", "cre"),
email = "caledo@uma.es")
as necessary.
CRAN incoming feasibility
Maintainer: ‘Juan Carlos Aledo <caledo@uma.es>’
No Authors@R field in DESCRIPTION.
Please add one, modifying
Authors@R: person(given = c("Juan", "Carlos"),
family = "Aledo",
role = c("aut", "cre"),
email = "caledo@uma.es")
as necessary.