refineR
Reference Interval Estimation using Real-World Data
Description
Indirect method for the estimation of reference intervals (RIs) using Real-World Data ('RWD') and methods for comparing and verifying RIs. Estimates RIs by applying advanced statistical methods to routine diagnostic test measurements, which include both pathological and non-pathological samples, to model the distribution of non-pathological samples. This distribution is then used to derive reference intervals and support RI verification, i.e., deciding if a specific RI is suitable for the local population. The package also provides functions for printing and plotting algorithm results. See ?refineR for a detailed description of features. Version 1.0 of the algorithm is described in 'Ammer et al. (2021)' <doi:10.1038/s41598-021-95301-2>. Additional guidance is in 'Ammer et al. (2023)' <doi:10.1093/jalm/jfac101>. The verification method is described in 'Beck et al. (2025)' <doi:10.1515/cclm-2025-0728>.
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Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | OK |
| r-devel-linux-x86_64-debian-gcc | OK |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | NOTE |
| r-oldrel-macos-x86_64 | NOTE |
| r-oldrel-windows-x86_64 | NOTE |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check details (3 non-OK)
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 3.5Mb
doc 1.8Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 3.5Mb
doc 1.8Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 3.5Mb
doc 1.8Mb
Check History
NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 3.5Mb
doc 1.8Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 3.5Mb
doc 1.8Mb
installed package size
installed size is 5.6Mb
sub-directories of 1Mb or more:
data 3.5Mb
doc 1.8Mb