Analyses of Protein Post-Translational Modifications
Overview
Contains utilities for the analysis of post-translational modifications (PTMs) in proteins, with particular emphasis on the sulfoxidation of methionine residues. Features include the ability to download, filter and analyze data from the sulfoxidation database 'MetOSite'. Utilities to search and characterize S-aromatic motifs in proteins are also provided. In addition, functions to analyze sequence environments around modifiable residues in proteins can be found. For instance, 'ptm' allows to search for amino acids either overrepresented or avoided around the modifiable residues from the proteins of interest. Functions tailored to test statistical hypothesis related to these differential sequence environments are also implemented. Further and detailed information regarding the methods in this package can be found in (Aledo (2020) https://metositeptm.com).
The structure of the package has been substantially simplified reducing multiples third parties dependencies in order to gain in robustness and portability. The focus has been put on the posttranslational modification of methionine. The users interested in the original functionality (extended utilities) still can opt to download one of the older version of the package at https://bitbucket.org/jcaledo/ptm.
From NEWS.md in the release
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK14 OK2026-03-10
Documentation
- Help pages
- 16
- Examples that run
- 62%8 run in a plain check · 5 never run
- Exported functions with examples
- 100%
- Documented parameters
- 94%
- Return-value docs
- 100%
- Help pages citing references
- 44%
Downloads
Repository
Repository github.com/jcaledo/rptm is linked, but repository-practices checks have not run for it yet.
Dependencies
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- 1.0.1Latest2024-05-21 · current release · diff ↗ ·
removed 57 exports
abundance, ac.scan, acc.dssp, atom.dpx, bg.go, ddG.profile, ddG.ptm, dis.scan, dpx, env.Ztest, env.extract, env.matrices, env.plot, find.aaindex, foldx.assembly, foldx.mut, foldx.stab, get.area, get.go, gl.scan, hdfisher.go, id.features, id.mapping, imutant, kegg.uniprot, me.scan, mkdssp, msa, net.go, ni.scan and 27 more - unarchivedReturned to CRAN2024-05-09
- 0.2.72024-05-09 · diff ↗
- archivedRemoved from CRAN2024-05-04issues were not corrected in time
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- 0.2.6
- RR 4.2.0 released · 2022-04-22
- 0.2.52022-02-14 · diff ↗
- 0.2.42021-05-24 · diff ↗
- RR 4.1.0 released · 2021-05-18
- 0.2.32021-05-09 · diff ↗ ·
removed 12 exports
ball, custom.aln, dist2closest, get.hssp, gorilla, list.hom, parse.hssp, pdb.pep, pdb.res, res.dist, shannon, site.typeadded 5 exports
gracefully_fail, kegg.uniprot, pdb.uniprot, uniprot.kegg, uniprot.pdb - 0.2.22020-12-16
- RR 4.0.0 released · 2020-04-24
Package metadata
- First published
- 2020-12-16
- Total releases
- 7 / 6 yrs
- License
- GPL (>= 2) OSI
- Minimum R
- ≥ 4.0.0
- Bundled data
- 212 KB / 1 file
- Download size
- 1.1 MB
Cite
Cite this package
Run in R for the authors' entry:
citation("ptm")The package provides a citation file, so citation() returns the authors' own entry.
It points to 10.1093/bioinformatics/btab348.
Cite the R Observatory
For a number measured here: a download total, a coverage figure, an archival date.
From data release v2026-10-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.