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Analyses of Protein Post-Translational Modifications

0packages depend
4Kdownloads / year
76.7%test coverage
13/13flavors OK

Overview

About

Contains utilities for the analysis of post-translational modifications (PTMs) in proteins, with particular emphasis on the sulfoxidation of methionine residues. Features include the ability to download, filter and analyze data from the sulfoxidation database 'MetOSite'. Utilities to search and characterize S-aromatic motifs in proteins are also provided. In addition, functions to analyze sequence environments around modifiable residues in proteins can be found. For instance, 'ptm' allows to search for amino acids either overrepresented or avoided around the modifiable residues from the proteins of interest. Functions tailored to test statistical hypothesis related to these differential sequence environments are also implemented. Further and detailed information regarding the methods in this package can be found in (Aledo (2020) https://metositeptm.com).

Changes in 1.0.1

The structure of the package has been substantially simplified reducing multiples third parties dependencies in order to gain in robustness and portability. The focus has been put on the posttranslational modification of methionine. The users interested in the original functionality (extended utilities) still can opt to download one of the older version of the package at https://bitbucket.org/jcaledo/ptm.

From NEWS.md in the release

Install

Health

CRAN checks
13OK
Slowest check: 1.4 min · r-oldrel-windows-x86_64
Status changes
  • OK13 OK2026-08-05
  • NOTE12 OK, 1 NOTE2026-08-01
  • OK14 OK2026-03-10
Advisories

none known

Documentation

In release 1.0.1
READMEYes · 113 wordsVignettesNoNEWSYes · 67% structured · mentions 1.0.1Citation fileYes · cites a publicationWebsiteYes
Help pages
16
Examples that run
62%8 run in a plain check · 5 never run
Exported functions with examples
100%
Documented parameters
94%
Return-value docs
100%
Help pages citing references
44%

Downloads

4K
CRAN downloads in the past year
Rank #10,151 · ~11/day · ~333/mo
Daily download trend is not available in this view yet.
36930 days
98290 days
4K1 year
Compare downloads with other packages →
Also on85 r2u43 c2d4u

Repository

Responsiveness
not measured
PracticesBeta

Repository github.com/jcaledo/rptm is linked, but repository-practices checks have not run for it yet.

How this is detected·Detection ruleset v3 (2026-09-26)

Dependencies

Declared dependencies
7 external dependencies (excludes base and recommended)

Installing ptm adds 10 packages (8 with compiled code, 6.3 MB of source tarballs). Heaviest: Rcpp 1.8 MB, bio3d 1.5 MB, openssl 1.1 MB.

Depends (1)
R >= 4.0.0
Imports (6)
LinkingTo (0)
none
Enhances (0)
none
Reverse dependencies
0direct
0indirect

Nothing depends on this yet.

Datasets

People & History

People (1)
Author, Maintainer since 0.2.2 (2020)
Releases (7)

Pick two releases to compare their code metrics.

  • R
    R 4.6.0 released · 2026-04-24
  • R
    R 4.5.0 released · 2025-04-11
  • 1.0.1Latest
    record
    2024-05-21 · current release · diff ↗ ·
    removed 57 exports
    abundance, ac.scan, acc.dssp, atom.dpx, bg.go, ddG.profile, ddG.ptm, dis.scan, dpx, env.Ztest, env.extract, env.matrices, env.plot, find.aaindex, foldx.assembly, foldx.mut, foldx.stab, get.area, get.go, gl.scan, hdfisher.go, id.features, id.mapping, imutant, kegg.uniprot, me.scan, mkdssp, msa, net.go, ni.scan and 27 more
  • unarchivedReturned to CRAN
    2024-05-09
  • 0.2.7
    record
    2024-05-09 · diff ↗
  • archivedRemoved from CRAN
    2024-05-04
    issues were not corrected in time
  • R
    R 4.4.0 released · 2024-04-24
  • R
    R 4.3.0 released · 2023-04-21
  • 0.2.6
    record
    2022-08-07 · diff ↗ ·
    removed 1 export
    compute.dssp
  • R
    R 4.2.0 released · 2022-04-22
  • 0.2.5
    record
    2022-02-14 · diff ↗
  • 0.2.4
    record
    2021-05-24 · diff ↗
  • R
    R 4.1.0 released · 2021-05-18
  • 0.2.3
    record
    2021-05-09 · diff ↗ ·
    removed 12 exports
    ball, custom.aln, dist2closest, get.hssp, gorilla, list.hom, parse.hssp, pdb.pep, pdb.res, res.dist, shannon, site.type
    added 5 exports
    gracefully_fail, kegg.uniprot, pdb.uniprot, uniprot.kegg, uniprot.pdb
  • 0.2.2
    record
    2020-12-16
  • R
    R 4.0.0 released · 2020-04-24

Package metadata

First published
2020-12-16
Total releases
7 / 6 yrs
License
GPL (>= 2) OSI
Minimum R
≥ 4.0.0
Bundled data
212 KB / 1 file
Download size
1.1 MB

Cite

Cite this package

Run in R for the authors' entry:

citation("ptm")

The package provides a citation file, so citation() returns the authors' own entry.

It points to 10.1093/bioinformatics/btab348.

Cite the R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA

Balamuta, J. J. (2026). R Observatory: Metrics for ptm version 1.0.1 [Data set]. HJJB, LLC. Data release v2026-10-18. https://doi.org/10.5281/zenodo.21843040

From data release v2026-10-18, which the citation names so these numbers can be found later. More on citing and the projects behind them.

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