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ofGEM

A Meta-Analysis Approach with Filtering for Identifying Gene-Level Gene-Environment Interactions with Genetic Association Data

v1.0 · Jul 13, 2018 · GPL

Description

Offers a gene-based meta-analysis test with filtering to detect gene-environment interactions (GxE) with association data, proposed by Wang et al. (2018) <doi:10.1002/gepi.22115>. It first conducts a meta-filtering test to filter out unpromising SNPs by combining all samples in the consortia data. It then runs a test of omnibus-filtering-based GxE meta-analysis (ofGEM) that combines the strengths of the fixed- and random-effects meta-analysis with meta-filtering. It can also analyze data from multiple ethnic groups.

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Maintainer: ‘Jiebiao Wang <randel.wang@gmail.com>’

No Authors@R field in DESCRIPTION.
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  Authors@R: c(person(given = "Jiebiao",
                      family = "Wang",
                      role = c("aut", "cre"),
                      email = "randel.wang@gmail.com"),
               person(given = "Qianying",
                      family = "Liu",
                      role = "aut"),
               person(given = c("Lin", "S."),
                      family = "Chen",
                      role = "aut"))
as necessary.
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CRAN incoming feasibility

Maintainer: ‘Jiebiao Wang <randel.wang@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Jiebiao",
                      family = "Wang",
                      role = c("aut", "cre"),
                      email = "randel.wang@gmail.com"),
               person(given = "Qianying",
                      family = "Liu",
                      role = "aut"),
               person(given = c("Lin", "S."),
                      family = "Chen",
                      role = "aut"))
as necessary.

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NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Jiebiao Wang <randel.wang@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Jiebiao",
                      family = "Wang",
                      role = c("aut", "cre"),
           
...[truncated]...
             person(given = "Qianying",
                      family = "Liu",
                      role = "aut"),
               person(given = c("Lin", "S."),
                      family = "Chen",
                      role = "aut"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Jiebiao Wang <randel.wang@gmail.com>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Jiebiao",
                      family = "Wang",
                      role = c("aut", "cre"),
           
...[truncated]...
             person(given = "Qianying",
                      family = "Liu",
                      role = "aut"),
               person(given = c("Lin", "S."),
                      family = "Chen",
                      role = "aut"))
as necessary.

Dependency Network

Dependencies Reverse dependencies CompQuadForm MASS forestplot ofGEM

Version History

1 tracked
new 1.0 Mar 10, 2026

R Observatory began tracking this package on Mar 10, 2026; it first appeared on CRAN Jul 13, 2018. Releases before tracking aren’t shown.