dtpcrm
Dose Transition Pathways for Continual Reassessment Method
v0.1.1
·
Aug 20, 2019
·
GPL (>= 2)
Description
Provides the dose transition pathways (DTP) to project in advance the doses recommended by a model-based design for subsequent patients (stay, escalate, deescalate or stop early) using all the accumulated toxicity information; See Yap et al (2017) <doi: 10.1158/1078-0432.CCR-17-0582>. DTP can be used as a design and an operational tool and can be displayed as a table or flow diagram. The 'dtpcrm' package also provides the modified continual reassessment method (CRM) and time-to-event CRM (TITE-CRM) with added practical considerations to allow stopping early when there is sufficient evidence that the lowest dose is too toxic and/or there is a sufficient number of patients dosed at the maximum tolerated dose.
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14
NOTE
Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | NOTE |
| r-devel-linux-x86_64-debian-gcc | NOTE |
| r-devel-linux-x86_64-fedora-clang | NOTE |
| r-devel-linux-x86_64-fedora-gcc | NOTE |
| r-devel-macos-arm64 | NOTE |
| r-devel-windows-x86_64 | NOTE |
| r-oldrel-macos-arm64 | NOTE |
| r-oldrel-macos-x86_64 | NOTE |
| r-oldrel-windows-x86_64 | NOTE |
| r-patched-linux-x86_64 | NOTE |
| r-release-linux-x86_64 | NOTE |
| r-release-macos-arm64 | NOTE |
| r-release-macos-x86_64 | NOTE |
| r-release-windows-x86_64 | NOTE |
Check details (17 non-OK)
NOTE
r-devel-linux-x86_64-debian-clang
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
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NOTE
r-devel-linux-x86_64-debian-gcc
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-linux-x86_64-fedora-clang
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-linux-x86_64-fedora-gcc
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-macos-arm64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-windows-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-oldrel-macos-arm64
LazyData
'LazyData' is specified without a 'data' directory
NOTE
r-oldrel-macos-arm64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-oldrel-macos-x86_64
LazyData
'LazyData' is specified without a 'data' directory
NOTE
r-oldrel-macos-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-oldrel-windows-x86_64
LazyData
'LazyData' is specified without a 'data' directory
NOTE
r-oldrel-windows-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-patched-linux-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-linux-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-macos-arm64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-macos-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-windows-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
Check History
NOTE 0 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
NOTE
r-devel-linux-x86_64-debian-clang
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-linux-x86_64-debian-gcc
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-linux-x86_64-fedora-clang
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-linux-x86_64-fedora-gcc
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-macos-arm64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-devel-windows-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-patched-linux-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-linux-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-macos-arm64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-macos-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-release-windows-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-oldrel-macos-arm64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-oldrel-macos-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^
NOTE
r-oldrel-windows-x86_64
Rd files
checkRd: (-1) applied_crm.Rd:64: Lost braces; missing escapes or markup?
64 | The empiric model is specified as F(d, beta) = d^{exp(beta)}. The logistic model is
| ^