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dfcomb

Phase I/II Adaptive Dose-Finding Design for Combination Studies

v3.1-5 · Mar 2, 2026 · GPL-3

Description

Phase I/II adaptive dose-finding design for combination studies where toxicity rates are supposed to increase with both agents.

Downloads

CRAN

384

Last 30 days

11301st

870

Last 90 days

3.6K

Last year

Trend: +64.8% (30d vs prior 30d)

r2u CRAN

24

Last 30 days

119

Last 90 days

430

Last year

Trend: -40% (30d vs prior 30d)

autoCRAN

4

Last 7 days

6

Last 30 days

2

All-time

autoCRAN-only: this name is served only by autoCRAN, so the count is exact.

CRAN Check Status

13 OK
Show all 13 flavors
Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Apr 22, 2026
ERROR 13 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Apr 18, 2026
ERROR r-devel-windows-x86_64

whether package can be installed

Installation failed.
See 'd:/Rcompile/CRANpkg/local/4.6/dfcomb.Rcheck/00install.out' for details.
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Apr 10, 2026
ERROR 13 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Apr 9, 2026
ERROR r-devel-linux-x86_64-debian-gcc

whether package can be installed

Installation failed.
See ‘/home/hornik/tmp/R.check/r-devel-gcc/Work/PKGS/dfcomb.Rcheck/00install.out’ for details.
OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Code

Structure

Lines of code

2,571

Files

13

Compiled share

70.5%

Has compiled src

Yes

Language breakdown

R 490 (19.1%)C/C++/src 1,813 (70.5%)Docs 268 (10.4%)

API

Exported functions

2

Internal functions

2

Recent export changes

v3.0-0−2 CombPlateau_sim, CombPlateau_next

Testing & CI

Has tests

No

Test-to-code ratio

0.00

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Return-value doc rate

100%

\dontrun example ratio

0%

Roxygen coverage

100%

Has pkgdown

No

NEWS present

No

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

3.2.3

System requirements

C++ standard

License

GPL-3

License flags

SPDX valid, OSI approved

History

Versions

19

First release

2014-11-03

Latest release

2026-03-02

Avg cadence

119 days

Cold removal rate

100%

Dep drift

0

LOC over versions

v1.0: 2,245 LOCv1.0-1: 2,245 LOCv2.0-2: 5,613 LOCv2.1: 5,604 LOCv2.1-1: 5,605 LOCv2.1-3: 5,614 LOCv2.1-4: 5,614 LOCv2.1-5: 5,588 LOCv2.1-6: 5,561 LOCv2.2: 5,563 LOCv2.3: 5,494 LOCv2.4: 5,494 LOCv2.4-2: 5,496 LOCv2.5-0: 5,490 LOCv2.6-0: 5,481 LOCv3.0-0: 2,561 LOCv3.1-1: 2,575 LOCv3.1-4: 2,575 LOCv3.1-5: 2,571 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/cran-code-metrics.

Version History

20 tracked
new 3.1-5 Mar 10, 2026
updated 3.1-5 ← 3.1-4 diff Mar 1, 2026
updated 3.1-4 ← 3.1-1 diff Sep 29, 2024
updated 3.1-1 ← 3.0-0 diff Jan 6, 2023
updated 3.0-0 ← 2.6-0 diff Mar 18, 2019
updated 2.6-0 ← 2.5-0 diff Feb 21, 2019
updated 2.5-0 ← 2.4-2 diff May 23, 2018
updated 2.4-2 ← 2.4 diff Jan 9, 2018
updated 2.4 ← 2.3 diff Jan 6, 2018
updated 2.3 ← 2.2 diff May 21, 2017
updated 2.2 ← 2.1-6 diff Mar 26, 2017
updated 2.1-6 ← 2.1-5 diff Jun 20, 2016
updated 2.1-5 ← 2.1-4 diff Oct 4, 2015
updated 2.1-4 ← 2.1-3 diff Sep 10, 2015
updated 2.1-3 ← 2.1-1 diff Apr 29, 2015