denovolyzeR
Statistical Analyses of De Novo Genetic Variants
Description
An integrated toolset for the analysis of de novo (sporadic) genetic sequence variants. denovolyzeR implements a mutational model that estimates the probability of a de novo genetic variant arising in each human gene, from which one can infer the expected number of de novo variants in a given population size. Observed variant frequencies can then be compared against expectation in a Poisson framework. denovolyzeR provides a suite of functions to implement these analyses for the interpretation of de novo variation in human disease.
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CRAN Check Status
Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | NOTE |
| r-devel-linux-x86_64-debian-gcc | NOTE |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check details (2 non-OK)
CRAN incoming feasibility
Maintainer: ‘James Ware <j.ware@imperial.ac.uk>’
Found the following URLs which should use \doi (with the DOI name only):
File ‘fmrpGenes.Rd’:
http://dx.doi.org/10.1016/j.cell.2011.06.013
CRAN incoming feasibility
Maintainer: ‘James Ware <j.ware@imperial.ac.uk>’
Found the following URLs which should use \doi (with the DOI name only):
File ‘fmrpGenes.Rd’:
http://dx.doi.org/10.1016/j.cell.2011.06.013
Check History
NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
CRAN incoming feasibility
Maintainer: ‘James Ware <j.ware@imperial.ac.uk>’
Found the following URLs which should use \doi (with the DOI name only):
File ‘fmrpGenes.Rd’:
http://dx.doi.org/10.1016/j.cell.2011.06.013
CRAN incoming feasibility
Maintainer: ‘James Ware <j.ware@imperial.ac.uk>’
Found the following URLs which should use \doi (with the DOI name only):
File ‘fmrpGenes.Rd’:
http://dx.doi.org/10.1016/j.cell.2011.06.013