crispRdesignR
Guide Sequence Design for CRISPR/Cas9
Description
Designs guide sequences for CRISPR/Cas9 genome editing and provides information on sequence features pertinent to guide efficiency. Sequence features include annotated off-target predictions in a user-selected genome and a predicted efficiency score based on the model described in Doench et al. (2016) <doi:10.1038/nbt.3437>. Users are able to import additional genomes and genome annotation files to use when searching and annotating off-target hits. All guide sequences and off-target data can be generated through the 'R' console with sgRNA_Design() or through 'crispRdesignR's' user interface with crispRdesignRUI(). CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and the associated protein Cas9 refer to a technique used in genome editing.
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CRAN Check Status
Show all 14 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | OK |
| r-devel-linux-x86_64-debian-gcc | OK |
| r-devel-linux-x86_64-fedora-clang | NOTE |
| r-devel-linux-x86_64-fedora-gcc | NOTE |
| r-devel-macos-arm64 | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | NOTE |
| r-oldrel-macos-x86_64 | NOTE |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check details (4 non-OK)
dependencies in R code
Namespace in Imports field not imported from: ‘DT’ All declared Imports should be used.
dependencies in R code
Namespace in Imports field not imported from: ‘DT’ All declared Imports should be used.
package dependencies
Package suggested but not available for checking: ‘BSgenome.Scerevisiae.UCSC.sacCer3’
package dependencies
Package suggested but not available for checking: ‘BSgenome.Scerevisiae.UCSC.sacCer3’
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NOTE 10 OK · 4 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
dependencies in R code
Namespace in Imports field not imported from: ‘DT’ All declared Imports should be used.
dependencies in R code
Namespace in Imports field not imported from: ‘DT’ All declared Imports should be used.
package dependencies
Package suggested but not available for checking: ‘BSgenome.Scerevisiae.UCSC.sacCer3’
package dependencies
Package suggested but not available for checking: ‘BSgenome.Scerevisiae.UCSC.sacCer3’