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aSPU

Adaptive Sum of Powered Score Test

v1.50 · Jun 28, 2021 · GPL-3

Description

R codes for the (adaptive) Sum of Powered Score ('SPU' and 'aSPU') tests, inverse variance weighted Sum of Powered score ('SPUw' and 'aSPUw') tests and gene-based and some pathway based association tests (Pathway based Sum of Powered Score tests ('SPUpath'), adaptive 'SPUpath' ('aSPUpath') test, 'GEEaSPU' test for multiple traits - single 'SNP' (single nucleotide polymorphism) association in generalized estimation equations, 'MTaSPUs' test for multiple traits - single 'SNP' association with Genome Wide Association Studies ('GWAS') summary statistics, Gene-based Association Test that uses an extended 'Simes' procedure ('GATES'), Hybrid Set-based Test ('HYST') and extended version of 'GATES' test for pathway-based association testing ('GATES-Simes'). ). The tests can be used with genetic and other data sets with covariates. The response variable is binary or quantitative. Summary; (1) Single trait-'SNP' set association with individual-level data ('aSPU', 'aSPUw', 'aSPUr'), (2) Single trait-'SNP' set association with summary statistics ('aSPUs'), (3) Single trait-pathway association with individual-level data ('aSPUpath'), (4) Single trait-pathway association with summary statistics ('aSPUsPath'), (5) Multiple traits-single 'SNP' association with individual-level data ('GEEaSPU'), (6) Multiple traits- single 'SNP' association with summary statistics ('MTaSPUs'), (7) Multiple traits-'SNP' set association with summary statistics('MTaSPUsSet'), (8) Multiple traits-pathway association with summary statistics('MTaSPUsSetPath').

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113

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Trend: -92.3% (30d vs prior 30d)

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9

Last 7 days

43

Last 30 days

3

All-time

autoCRAN-only: this name is served only by autoCRAN, so the count is exact.

CRAN Check Status

2 NOTE
11 OK
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r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
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r-patched-linux-x86_64 OK
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r-release-windows-x86_64 OK
Check details (2 non-OK)
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CRAN incoming feasibility

Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’

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  Authors@R: c(person(given = "Il-Youp",
                      family = "Kwak",
                      role = c("aut", "cre"),
                      email = "ikwak2@cau.ac.kr"),
               person(given = c("others", "in", "each", "function"),
                      family = "manual)",
                      role = "aut",
                      comment = "s"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Il-Youp",
                      family = "Kwak",
                      role = c("aut", "cre"),
                      email = "ikwak2@cau.ac.kr"),
               person(given = c("others", "in", "each", "function"),
                      family = "manual)",
                      role = "aut",
                      comment = "s"))
as necessary.

Check History

NOTE 12 OK · 2 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
NOTE r-devel-linux-x86_64-debian-clang

CRAN incoming feasibility

Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Il-Youp",
                      family = "Kwak",
                      role = c("aut", "cre"),
                      email = "ikwak2@cau.ac.kr"),
               person(given = c("others", "in", "each", "function"),
                      family = "manual)",
                      role = "aut",
                      comment = "s"))
as necessary.
NOTE r-devel-linux-x86_64-debian-gcc

CRAN incoming feasibility

Maintainer: ‘Il-Youp Kwak <ikwak2@cau.ac.kr>’

No Authors@R field in DESCRIPTION.
Please add one, modifying
  Authors@R: c(person(given = "Il-Youp",
                      family = "Kwak",
                      role = c("aut", "cre"),
                      email = "ikwak2@cau.ac.kr"),
               person(given = c("others", "in", "each", "function"),
                      family = "manual)",
                      role = "aut",
                      comment = "s"))
as necessary.

Code

Structure

Lines of code

6,674

Files

80

Compiled share

0%

Has compiled src

No

Language breakdown

R 4,674 (70%)Docs 1,641 (24.6%)Vignettes 359 (5.4%)

API

Exported functions

24

Internal functions

24

Recent export changes

v1.47+2 aSPUpath2, aSPUsPath2  −1 MTaSPUsSetC

Testing & CI

Has tests

No

Test-to-code ratio

0.00

testthat edition

CI present

No

CI type

[]

PR gated

No

Docs

Return-value doc rate

100%

\dontrun example ratio

0%

Roxygen coverage

100%

Has pkgdown

No

NEWS present

No

Health & Security signals

Informational signals; not verdicts.

on.exit coverage

Unsafe pattern score

0

Dep constraint coverage

0%

Secret pattern count

0

Bundled 3rd-party code

2 items

Portability & License

Min R version

3.6.0

System requirements

C++ standard

License

GPL-3

License flags

SPDX valid, OSI approved

History

Versions

17

First release

2015-05-28

Latest release

2021-06-28

Avg cadence

48 days

Cold removal rate

100%

Dep drift

7

LOC over versions

v1.33: 3,141 LOCv1.35: 3,141 LOCv1.36: 3,932 LOCv1.37: 3,924 LOCv1.38: 4,195 LOCv1.39: 4,635 LOCv1.40: 4,674 LOCv1.41: 4,790 LOCv1.42: 6,024 LOCv1.43: 6,693 LOCv1.44: 7,157 LOCv1.45: 7,159 LOCv1.46: 7,174 LOCv1.47: 6,530 LOCv1.48: 6,528 LOCv1.49: 6,674 LOCv1.50: 6,674 LOC

Per-file churn detail lives in the source pipeline: https://github.com/r-observatory/cran-code-metrics.

Dependency Network

Dependencies Reverse dependencies gee MASS mvtnorm fields matrixStats aSPU

Version History

18 tracked
new 1.50 Mar 10, 2026
updated 1.50 ← 1.49 diff Jun 27, 2021
updated 1.49 ← 1.48 diff May 12, 2020
updated 1.48 ← 1.47 diff Jun 24, 2017
updated 1.47 ← 1.46 diff May 20, 2017
updated 1.46 ← 1.45 diff Nov 8, 2016
updated 1.45 ← 1.44 diff Oct 11, 2016
updated 1.44 ← 1.43 diff Sep 21, 2016
updated 1.43 ← 1.42 diff Sep 14, 2016
updated 1.42 ← 1.41 diff May 2, 2016
updated 1.41 ← 1.40 diff Mar 21, 2016
updated 1.40 ← 1.39 diff Feb 17, 2016
updated 1.39 ← 1.38 diff Dec 21, 2015
updated 1.38 ← 1.37 diff Oct 25, 2015
updated 1.37 ← 1.36 diff Aug 2, 2015