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SpaCCI

Spatially Aware Cell-Cell Interaction Analysis

v1.0.5 · Feb 27, 2026 · GPL (>= 2)

Description

Provides tools for analyzing spatial cell-cell interactions based on ligand-receptor pairs, including functions for local, regional, and global analysis using spatial transcriptomics data. Integrates with databases like 'CellChat' <https://github.com/jinworks/CellChat>, 'CellPhoneDB' <https://www.cellphonedb.org/>, 'Cellinker' <https://www.rna-society.org/cellinker/>, 'ICELLNET' <https://github.com/soumelis-lab/ICELLNET>, and 'ConnectomeDB' <https://humanconnectome.org/software/connectomedb/> to identify ligand-receptor pairs, visualize interactions through heatmaps, chord diagrams, and infer interactions on different spatial scales.

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CRAN Check Status

7 NOTE
7 OK
Show all 14 flavors
Flavor Status
r-devel-linux-x86_64-debian-clang NOTE
r-devel-linux-x86_64-debian-gcc NOTE
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 NOTE
r-oldrel-macos-arm64 NOTE
r-oldrel-macos-x86_64 NOTE
r-oldrel-windows-x86_64 NOTE
r-patched-linux-x86_64 NOTE
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK
Check details (7 non-OK)
NOTE r-devel-linux-x86_64-debian-clang

compiled code

File ‘SpaCCI/libs/SpaCCI.so’:
  Found non-API call to R: ‘R_UnboundValue’

Compiled code should not call non-API entry points in R.

See ‘Writing portable packages’ in the ‘Writing R Extensions’ manual,
and section ‘Moving into C API compliance’ for issues with the use of
non-API entry points.
NOTE r-devel-linux-x86_64-debian-gcc

compiled code

File ‘SpaCCI/libs/SpaCCI.so’:
  Found non-API call to R: ‘R_UnboundValue’

Compiled code should not call non-API entry points in R.

See ‘Writing portable packages’ in the ‘Writing R Extensions’ manual,
and section ‘Moving into C API compliance’ for issues with the use of
non-API entry points.
NOTE r-devel-windows-x86_64

compiled code

File 'SpaCCI/libs/x64/SpaCCI.dll':
  Found non-API call to R: 'R_UnboundValue'

Compiled code should not call non-API entry points in R.

See 'Writing portable packages' in the 'Writing R Extensions' manual,
and section 'Moving into C API compliance' for issues with the use of
non-API entry points.
NOTE r-oldrel-macos-arm64

installed package size

installed size is  8.3Mb
  sub-directories of 1Mb or more:
    extdata   5.9Mb
    libs      1.9Mb
NOTE r-oldrel-macos-x86_64

installed package size

installed size is  8.4Mb
  sub-directories of 1Mb or more:
    extdata   5.9Mb
    libs      2.0Mb
NOTE r-oldrel-windows-x86_64

installed package size

installed size is  7.3Mb
  sub-directories of 1Mb or more:
    extdata   6.0Mb
    libs      1.0Mb
NOTE r-patched-linux-x86_64

compiled code

File ‘SpaCCI/libs/SpaCCI.so’:
  Found non-API call to R: ‘R_UnboundValue’

Compiled code should not call non-API entry points in R.

See ‘Writing portable packages’ in the ‘Writing R Extensions’ manual,
and section ‘Moving into C API compliance’ for issues with the use of
non-API entry points.

Check History

NOTE 11 OK · 3 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026
NOTE r-oldrel-macos-arm64

installed package size

installed size is  8.3Mb
  sub-directories of 1Mb or more:
    extdata   5.9Mb
    libs      1.9Mb
NOTE r-oldrel-macos-x86_64

installed package size

installed size is  8.4Mb
  sub-directories of 1Mb or more:
    extdata   5.9Mb
    libs      2.0Mb
NOTE r-oldrel-windows-x86_64

installed package size

installed size is  7.3Mb
  sub-directories of 1Mb or more:
    extdata   6.0Mb
    libs      1.0Mb

Dependency Network

Dependencies Reverse dependencies Rcpp Seurat nnls ggrepel pheatmap circlize Matrix dplyr patchwork reshape2 ggplot2 FNN rlang SpaCCI

Version History

new 1.0.5 Mar 10, 2026
updated 1.0.5 ← 1.0.4 diff Feb 26, 2026
updated 1.0.4 ← 1.0.3 diff May 11, 2025
updated 1.0.3 ← 1.0.2 diff Jan 18, 2025
updated 1.0.2 ← 1.0 diff Oct 23, 2024
new 1.0 Sep 29, 2024