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RTSA

'Trial Sequential Analysis' for Error Control and Inference in Sequential Meta-Analyses

v0.2.2 · Nov 23, 2023 · GPL (>= 2)

Description

Frequentist sequential meta-analysis based on 'Trial Sequential Analysis' (TSA) in programmed in Java by the Copenhagen Trial Unit (CTU). The primary function is the calculation of group sequential designs for meta-analysis to be used for planning and analysis of both prospective and retrospective sequential meta-analyses to preserve type-I-error control under sequential testing. 'RTSA' includes tools for sample size and trial size calculation for meta-analysis and core meta-analyses methods such as fixed-effect and random-effects models and forest plots. TSA is described in Wetterslev et. al (2008) <doi:10.1016/j.jclinepi.2007.03.013>. The methods for deriving the group sequential designs are based on Jennison and Turnbull (1999, ISBN:9780849303166).

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CRAN Check Status

14 OK
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r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Dependency Network

Dependencies Reverse dependencies metafor ggplot2 scales Rcpp RTSA

Version History

new 0.2.2 Mar 10, 2026
updated 0.2.2 ← 0.2.1 diff Nov 22, 2023
updated 0.2.1 ← 0.2.0 diff Aug 29, 2023
updated 0.2.0 ← 0.1.0 diff Aug 24, 2023
new 0.1.0 May 11, 2023