This package was removed from CRAN on 2026-05-06. Its history is shown below.
Reason: email to the maintainer is undeliverable
Details below reflect version 1.5, its last release before removal.
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1.5Simulates SPSO and Efftox Phase 12 Trials with Correlated Outcomes
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1.9Kdownloads / year
–test coverage
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Overview
About
Simulating and conducting four phase 12 clinical trials with correlated binary bivariate outcomes described. Uses the 'Efftox' (efficacy and toxicity tradeoff, https://biostatistics.mdanderson.org/SoftwareDownload/SingleSoftware/Index/2) and SPSO (Semi-Parametric Stochastic Ordering) models with Utility and Desirability based objective functions for dose finding.
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Check history
- NOTE2026-04-220 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
- ERROR2026-04-180 OK · 13 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE
- NOTE2026-03-100 OK · 14 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE
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Downloads
1.9K
CRAN downloads in the past year
Rank #24,559 · ~5/day · ~156/mo
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Also on403 r2u24 autocran
Dependencies
Declared dependencies
4 external dependencies (excludes base and recommended)
Depends (0)
none
LinkingTo (2)
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none
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none
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Code & Tests
People & History
Package Timeline
5 releases. R releases are shown for context.
- archivedRemoved from CRAN2026-05-06email to the maintainer is undeliverable
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- 1.52020-07-31 · diff ↗
- RR 4.0.0 released · 2020-04-24
- 1.32019-10-03 · diff ↗
- 1.22019-09-23 · diff ↗
- unarchivedReturned to CRAN2019-09-23
- archivedRemoved from CRAN2019-09-08use of uninitialized memory was not corrected by update
- 1.12019-09-05 · diff ↗
- 1.02019-08-30
- RR 3.6.0 released · 2019-04-26
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Package metadata
- Total releases
- 5
- License
- GPL-2 OSI
- Download size
- 33 KB
- Installed size
- not tracked yet
- With dependencies
- not tracked yet