NAPrior
Network Meta-Analytic Predictive Prior for Mid-Trial SoC Changes
v0.2.0
·
Feb 14, 2026
·
MIT + file LICENSE
Description
Implements the Network meta-Analytic Predictive (NAP) prior framework to accommodate changes in the standard of care (SoC) during ongoing randomized controlled trials (RCTs). The method synthesizes pre- and post-change in-trial data by leveraging external evidence, particularly head-to-head trials comparing the original and new standards of care, to bridge the two evidence periods and enable principled borrowing. The package provides utilities to construct NAP-based priors and perform Bayesian inference for time-to-event endpoints using summarized trial evidence.
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