Gaussian Mixture Model for Multi-Omics Data Integration
Overview
A multivariate Gaussian mixture model framework to integrate multiple types of genomic data and allow modeling of inter-data-type correlations for association analysis. 'IMIX' can be implemented to test whether a disease is associated with genes in multiple genomic data types, such as DNA methylation, copy number variation, gene expression, etc. It can also study the integration of multiple pathways. 'IMIX' uses the summary statistics of association test outputs and conduct integration analysis for two or three types of genomics data. 'IMIX' features statistically-principled model selection, global FDR control and computational efficiency. Details are described in Ziqiao Wang and Peng Wei (2020) doi:10.1093/bioinformatics/btaa1001.
Install
Health
- OK13 OK2026-08-05
- NOTE12 OK, 1 NOTE2026-08-01
- OK13 OK2026-06-09
- ERROR12 OK, 1 ERROR2026-06-08
- OK14 OK2026-03-10
Documentation
- Help pages
- 11
- Examples that run
- 33%2 run in a plain check · 4 only when donttest examples are enabled (R CMD check --as-cran)
- Exported functions with examples
- 60%
- Documented parameters
- 98%
- Return-value docs
- 100%
- Help pages citing references
- 91%
Downloads
Repository
Stars over time
Forks over time
1 development-tooling and community-health practice detected across 1 family in the upstream repository
Checks run against github.com/ziqiaow/imix on 2026-10-18.
Dependencies
Installing IMIX adds 70 packages (39 with compiled code, 69 MB of source tarballs). Heaviest: stringi 11 MB, ggplot2 6.0 MB, data.table 5.7 MB.
Code & Tests
Datasets
People & History
Pick two releases to compare their code metrics.
- RR 4.6.0 released · 2026-04-24
- RR 4.5.0 released · 2025-04-11
- RR 4.4.0 released · 2024-04-24
- RR 4.3.0 released · 2023-04-21
- 1.1.5Latest
- RR 4.2.0 released · 2022-04-22
- RR 4.1.0 released · 2021-05-18
- unarchivedReturned to CRAN2021-02-10
- 1.1.42021-02-10 · diff ↗
- archivedRemoved from CRAN2021-01-29check problems were not corrected in time
- 1.1.02020-12-08
- RR 4.0.0 released · 2020-04-24
Package metadata
- First published
- 2020-12-08
- Total releases
- 3 / 6 yrs
- License
- GPL-2 OSI
- Minimum R
- ≥ 3.5
- Bundled data
- 20 KB / 1 file
- Download size
- 42 KB
Cite
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Run in R for the authors' preferred citation:
citation("IMIX")This package has no citation file, so citation() returns this entry built from DESCRIPTION.
Cite the R Observatory
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