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HMC

High-Dimensional Mean Comparison with Projection and Cross-Fitting

v1.2 · May 2, 2025 · GPL-2

Description

Provides interpretable high-dimensional mean comparison methods (HMC). For example, users can apply these methods to assess the difference in gene expression between two treatment groups. It is not a gene-by-gene comparison. Instead, the methods focus on the interplay between features and identify those that are predictive of the group label. The tests are valid frequentist procedures and yield sparse estimates indicating which features contribute to the group differences.

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CRAN Check Status

14 OK
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Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Dependency Network

Dependencies Reverse dependencies glmnet irlba PMA MASS grpreg HMC

Version History

new 1.2 Mar 10, 2026
updated 1.2 ← 1.1 diff May 1, 2025
updated 1.1 ← 1.0 diff Aug 16, 2024
new 1.0 Mar 8, 2024