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DIscBIO

A User-Friendly Pipeline for Biomarker Discovery in Single-Cell Transcriptomics

v1.2.3 · Jan 8, 2026 · MIT + file LICENSE

Description

An open, multi-algorithmic pipeline for easy, fast and efficient analysis of cellular sub-populations and the molecular signatures that characterize them. The pipeline consists of four successive steps: data pre-processing, cellular clustering with pseudo-temporal ordering, defining differential expressed genes and biomarker identification. More details on Ghannoum et. al. (2021) <doi:10.3390/ijms22031399>. This package implements extensions of the work published by Ghannoum et. al. (2019) <doi:10.1101/700989>.

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r-devel-macos-arm64 OK
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ERROR r-oldrel-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-x86_64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-windows-x86_64

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ERROR 9 OK · 0 NOTE · 0 WARNING · 5 ERROR · 0 FAILURE Mar 10, 2026
ERROR r-devel-windows-x86_64

whether package can be installed

Installation failed.
See 'd:/Rcompile/CRANpkg/local/4.6/DIscBIO.Rcheck/00install.out' for details.
ERROR r-release-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-macos-x86_64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.
ERROR r-release-windows-x86_64

whether package can be installed

Installation failed.
See 'd:/Rcompile/CRANpkg/local/4.5/DIscBIO.Rcheck/00install.out' for details.
ERROR r-oldrel-macos-arm64

package dependencies

Package required but not available: ‘TSCAN’

See section ‘The DESCRIPTION file’ in the ‘Writing R Extensions’
manual.

Dependency Network

Dependencies Reverse dependencies SingleCellExperiment TSCAN httr mclust statmod igraph RWeka vegan NetIndices png RColorBrewer ggplot2 rpart fpc cluster +4 more dependencies DIscBIO

Version History

new 1.2.3 Mar 10, 2026
updated 1.2.3 ← 1.2.2 diff Jan 7, 2026
updated 1.2.2 ← 1.2.1 diff Nov 5, 2023
updated 1.2.1 ← 1.2.0 diff Oct 8, 2023
updated 1.2.0 ← 1.1.0 diff Apr 27, 2021
updated 1.1.0 ← 1.0.1 diff Nov 12, 2020
updated 1.0.1 ← 1.0.0 diff Oct 5, 2020
new 1.0.0 Aug 25, 2020