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Certara.NLME8

Utilities for Certara's Nonlinear Mixed-Effects Modeling Engine

v3.0.2 · Aug 19, 2025 · LGPL-3

Description

Perform Nonlinear Mixed-Effects (NLME) Modeling using Certara's NLME-Engine. Access the same Maximum Likelihood engines used in the Phoenix platform, including algorithms for parametric methods, individual, and pooled data analysis. The Quasi-Random Parametric Expectation-Maximization Method (QRPEM) is also supported <https://www.page-meeting.org/default.asp?abstract=2338>. Execution is supported both locally or on remote machines. Remote execution includes support for Linux Sun Grid Engine (SGE), Simple Linux Utility for Resource Management (SLURM) grids, Linux and Windows multicore, and individual runs.

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CRAN Check Status

14 OK
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Flavor Status
r-devel-linux-x86_64-debian-clang OK
r-devel-linux-x86_64-debian-gcc OK
r-devel-linux-x86_64-fedora-clang OK
r-devel-linux-x86_64-fedora-gcc OK
r-devel-macos-arm64 OK
r-devel-windows-x86_64 OK
r-oldrel-macos-arm64 OK
r-oldrel-macos-x86_64 OK
r-oldrel-windows-x86_64 OK
r-patched-linux-x86_64 OK
r-release-linux-x86_64 OK
r-release-macos-arm64 OK
r-release-macos-x86_64 OK
r-release-windows-x86_64 OK

Check History

OK 14 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Mar 10, 2026

Reverse Dependencies (2)

Dependency Network

Dependencies Reverse dependencies xml2 batchtools reshape data.table Certara.RsNLME Certara.RsNLME.ModelExecutor Certara.NLME8

Version History

new 3.0.2 Mar 10, 2026
updated 3.0.2 ← 3.0.1 diff Aug 19, 2025
updated 3.0.1 ← 1.2.4 diff Oct 14, 2024
updated 1.2.4 ← 1.2.3 diff Jun 14, 2023
new 1.2.3 May 17, 2023