BioUtils
Biological Data Analysis and Visualization
Description
Provides tools for the analysis and visualization of gene expression data from the NCBI Gene Expression Omnibus (GEO). Implements a complete workflow including data import, quality control, differential expression analysis, co-expression network analysis, pathway enrichment, and multi-gene biomarker discovery. Differential expression uses the empirical Bayes moderated t-statistic of Smyth (2004) <doi:10.2202/1544-6115.1027>. Gene set enrichment analysis follows Subramanian et al. (2005) <doi:10.1073/pnas.0506580102>. Multi-gene biomarker selection uses the LASSO method of Tibshirani (1996) <doi:10.1111/j.2517-6161.1996.tb02080.x>. Effect sizes are computed as Cohen's d following Cohen (1988).
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CRAN Check Status
Show all 13 flavors
| Flavor | Status |
|---|---|
| r-devel-linux-x86_64-debian-clang | OK |
| r-devel-linux-x86_64-debian-gcc | OK |
| r-devel-linux-x86_64-fedora-clang | OK |
| r-devel-linux-x86_64-fedora-gcc | OK |
| r-devel-windows-x86_64 | OK |
| r-oldrel-macos-arm64 | OK |
| r-oldrel-macos-x86_64 | OK |
| r-oldrel-windows-x86_64 | OK |
| r-patched-linux-x86_64 | OK |
| r-release-linux-x86_64 | OK |
| r-release-macos-arm64 | OK |
| r-release-macos-x86_64 | OK |
| r-release-windows-x86_64 | OK |
Check History
OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 26, 2026
ERROR 12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Jun 25, 2026
re-building of vignette outputs
Error(s) in re-building vignettes: ... --- re-building ‘bioutils-case-study.Rmd’ using rmarkdown --- finished re-building ‘bioutils-case-study.Rmd’ --- re-building ‘rcc-visual-analytics.Rmd’ using rmarkdown Quitting from rcc-visual-analytics.Rmd: ...[truncated]... ftp.ncbi.nlm.nih.gov]: Connection timed out after 120000 milliseconds --- failed re-building ‘rcc-visual-analytics.Rmd’ SUMMARY: processing the following file failed: ‘rcc-visual-analytics.Rmd’ Error: Vignette re-building failed. Execution halted
OK 13 OK · 0 NOTE · 0 WARNING · 0 ERROR · 0 FAILURE Jun 9, 2026
ERROR 12 OK · 0 NOTE · 0 WARNING · 1 ERROR · 0 FAILURE Jun 8, 2026
whether package can be installed
install log ‘’ does not exist