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SPsimSeq

1.22.0Bioconductor

Semi-parametric simulation tool for bulk and single-cell RNA sequencing data

BiocManager::install("SPsimSeq")
Distinct IPs a month, method
592Rank 1,461 in its category
Bioconductor releases
12since 2020
Advisories, method
None publishedfor Bioconductor

SPsimSeq uses a specially designed exponential family for density estimation to constructs the distribution of gene expression levels from a given real RNA sequencing data (single-cell or bulk), and subsequently simulates a new dataset from the estimated marginal distributions using ...

Full description

SPsimSeq uses a specially designed exponential family for density estimation to constructs the distribution of gene expression levels from a given real RNA sequencing data (single-cell or bulk), and subsequently simulates a new dataset from the estimated marginal distributions using Gaussian-copulas to retain the dependence between genes. It allows simulation of multiple groups and batches with any required sample size and library size.

Maintainer
Joris Meys
Licence
GPL-2
Last updated
28 Apr 2026
First release
Bioconductor 3.12, 28 Oct 2020

Compare with another package

More details
Releases
12 of 49 Bioconductor releases
Category
software
Needs R
>= 4.0
LazyData
true
RoxygenNote
7.1.0
biocViews (5)
Cite

Package

Run in R for the authors' preferred citation:

citation("SPsimSeq")

The package provides a citation file that builds its entry when R runs it. Run citation() to see it.

R Observatory

For a number measured here: a download total, a coverage figure, an archival date.

APA
Balamuta, J. J. (2026). R Observatory: Metrics for SPsimSeq version 1.22.0 [Data set]. HJJB, LLC. Data release v2026-10-27. https://doi.org/10.5281/zenodo.21843040
About

From data release v2026-10-27, which the citation names so these numbers can be found later.

Release 3.23: OK 23 Oct 2026

  • kunpeng2, Install

    Install on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.22.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • kunpeng2, Build

    Build on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.22.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • kunpeng2, Check

    Check on the build machine kunpeng2. Bioconductor release 3.23.

    OK

    Version built
    1.22.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • nebbiolo1, Install

    Install on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.22.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • nebbiolo1, Build

    Build on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.22.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • nebbiolo1, Check

    Check on the build machine nebbiolo1. Bioconductor release 3.23.

    OK

    Version built
    1.22.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    23 Oct 2026
  • 6 OK
Machines (2)
MachineInstallBuildCheck
kunpeng2OKOKOK
nebbiolo1OKOKOK
Devel 3.24: Timeout
  • lconway, Check

    Check on the build machine lconway. The next Bioconductor release, 3.24.

    Timeout

    Version built
    1.23.0
    In this state since
    23 Oct 2026
    Last seen
    25 Oct 2026
  • lconway, Install

    Install on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • lconway, Build

    Build on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • lconway, Build binary

    Build binary on the build machine lconway. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • nebbiolo2, Install

    Install on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • nebbiolo2, Build

    Build on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • nebbiolo2, Check

    Check on the build machine nebbiolo2. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • taishan, Install

    Install on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • taishan, Build

    Build on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • taishan, Check

    Check on the build machine taishan. The next Bioconductor release, 3.24.

    OK

    Version built
    1.23.0
    In this state since
    29 Sep 2026 or earlier
    Last seen
    25 Oct 2026
  • 1 Timeout
  • 9 OK
MachineInstallBuildCheckBuild binary
lconwayOKOKTimeoutOK
nebbiolo2OKOKOK
taishanOKOKOK
Built files (4)
PlatformKindFile
macOS (Intel)binarySPsimSeq_1.22.0.tgz
macOS (Apple Silicon)binarySPsimSeq_1.22.0.tgz
sourcesourceSPsimSeq_1.22.0.tar.gz
WindowsbinarySPsimSeq_1.22.0.zip
Total downloads in the latest complete month
4,563It comes from Bioconductor alone. Bioconda was counted over another window, so it is not added.

Rank in category, by distinct IPs

1,461 of 3,170

Bioconductor

4,563 downloads in the latest complete month

Distinct IP addresses average 592 a month over 12 months, which is a different measure and is never added.

It is in the total. Take it out

Bioconda

48 downloads in the last 30 days

It is not added because it has no figure for the latest complete month.

This local copy has no series over time.

Compare downloads

Needs
12
Dependent packages
10 on CRAN, 1 on Bioconductor
Suggested by
1
Needs (12)
Needed in total
119 packages
Optional extras (5)
Dependent packages (1)
Functions
25
Public exports
3
Lines of R code
1,047
Median complexity
2
Functions (25)
Size and composition

Lines by kind (2,573)

KindLinesShare
R code1,04741%
Tests1285%
Documentation98338%
Guides41516%

Lines by language

LanguageLinesShare
R1,17546%
Rd98338%
Vignettes33413%
Other813%

Languages are counted from file extensions.

Files
72
R functions
25
Object systems
S4: 1 generics, S4: 4 methods
Complexity
Median
2
Mean
4
Highest
23
Median lines per function
15
About complexity

Cyclomatic complexity counts the independent paths through a function: 1 is a straight line, higher is harder to test. R functions only.

Call graph figures
R functions
25
Calls
27
Unconnected
0
Groups
1
Growth (12 releases)
Total lines by release
2,573 on 27 Oct 20202,573 on 28 Apr 2026
Release changes

Test coverage is measured for CRAN packages only. Nothing is known for Bioconductor packages, which is not the same as no coverage.

Test cases
7
Lines of tests
128
Exports named in tests
66.7%
Has tests
Yes
Test frameworks
testthat
Test lines per line of code
0.12
Exports documented
100%
Arguments documented
74.3%
Return value documented
100%
Help pages with examples
17.2%
Examples run in checks
100%
Guides (1)
Other documentation
README
No
Release notes file
Yes
Help pages
29
Lines of documentation
983
DatasetSize
scNGP.dataNeuroblastoma NGP cells single-cell RNA-seq.
zhang.data.subNeuroblastoma bulk RNA-seq data retrieved from Zhang et (2015).length 2

CenterForStatistics-UGent / spsimseq on github.com

Stars
10
Forks
4
Open issues
4
Last commit
17 Nov 2024
Activity
Commits
142
Open pull requests
0
Tagged releases
2
Latest tagged release
v2.0.0, 29 Nov 2019
Issues closed in
43 days (median)
Pull requests closed in
0 days (median)
Pull requests merged
83%
Created
7 Feb 2019
Licence file reads as
–
Development practices (1)

Bioconductor git

R releases
  • In Bioconductor
  • Bioconductor release
ReleaseReleasedR
3.23 current29 Apr 20264.6
3.2230 Oct 20254.5
3.2116 Apr 20254.5
3.2030 Oct 20244.4
3.191 May 20244.4
3.1825 Oct 20234.3
3.1726 Apr 20234.3
3.162 Nov 20224.2
Earlier releases (4)
ReleaseReleasedR
3.1527 Apr 20224.2
3.1427 Oct 20214.1
3.1320 May 20214.1
3.1228 Oct 20204.0
Entered Bioconductor
Release 3.12, 28 Oct 2020