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ModCon

Bioc current

Modifying splice site usage by changing the mRNP code, while maintaining the genetic code

v1.20.0 · software · GPL-3 + file LICENSE
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Release Lineage

Entered 3.13 · May 20, 2021

Current · Requires R 4.6

1.0 In 11 of 49 releases 3.23

Description

Collection of functions to calculate a nucleotide sequence surrounding for splice donors sites to either activate or repress donor usage. The proposed alternative nucleotide sequence encodes the same amino acid and could be applied e.g. in reporter systems to silence or activate cryptic splice donor sites.

Code & tests

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Topics

Software › ResearchField › FunctionalGenomics
Software › BiologicalQuestion › AlternativeSplicing

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